Conclusion

In conclusion, taking all the literature into account, it has been demonstrated that there is no evidence to support the presence of bacteria in the placenta and there is no significant relationship between the pregnancy complication like preeclampsia, SGA and preterm birth with the bacteria. However, most important pathogen called as S. agalactiae is present in the placenta of the pregnant women only about 5percent in women before the onset of labour.The placenta has sterile environment and so there is no alteration or placental microbiome because it totally not exists in the pregnant women.

References:

Aagaard, Kjersti, Ma, J., Antony, K. M., Ganu, R., & Joseph Petrosino, a. J. (2014). “The placenta harbors a unique microbiome. Science translational medicine 6, no. 237, pp. 237ra65-237ra65.

Goffau, e., C., M., Lager, S., Sovio, U., Gaccioli, F., Cook, E., . . . Smith, G. C. (2019). Human placenta has no microbiome but can contain potential pathogens. Nature 572 no. 7769, pp. 329-334.

Kuperman, A., A, Z., S, H., O, Z., V, G., B, F., . . . S., S. (2020 Jan). Deep microbial analysis of multiple placentas shows no evidence for a placental microbiome. BJOG: An International Journal of Obstetrics & Gynaecology, 159-69.

Parnell, A, L., Briggs, a. M., Ca, B., Delannoy-Bruno, O., Schrieffer, A. E., & Mysorekar., I. U. (2017). Microbial communities in placentas from term normal pregnancy exhibit spatially variable profiles. Scientific reports 7, no. 1, pp. 1-11.

Pelzer, Elise, F, L., Gomez-Arango, L, H., Barrett, & Nitert, a. M. (2017). Maternal health and the placental microbiome. Placenta 54 , pp. 30-37.

Salter, J., S., Cox, M. J., Turek, E. M., Calus, S. T., Cookson, W. O., . . . Walker., A. W. (2014). Reagent and laboratory contamination can critically impact sequence-based microbiome analyses. BMC biology 12, p. 87.

Singh, Bhuchitra, & Xia., P. (2019). “Placental Microbiome and Its Association With Preterm Labor-Systematic Literature Review. Biomedical Journal of Scientific & Technical Research 17, pp. 12598-12602.

Leave a Comment

Your email address will not be published. Required fields are marked *