The Complexity ofthe Stomach micro biome

Introduction:

The word microbiota represents an ensemble of microorganisms that resides in a previously established environment. Human beings have clusters of bacteria in different parts of the body such as in the surface or deep layers of skin (skin microbiota), the mouth (oral microbiota), the vagina (vaginal micro biota), and so on (Eckburg, P. B., et al 2005).

Stomach microbiome is an important microbiome but it lacks significant microbiome because of hostile environment. It is noted that very low pH and tight immune system restricted organism entry into stomach. The Stomach microbiota belongs to major 5 phyla and 100 of phylotypes e.g. Bacteroidetes, Firmicutes, Proteobacteria, Actinobacteria, and Fusobacteria(Wang, B., et al 2017).Discovery of Helicobacter Pylori changed the views on Microbiota of Stomach.H.pylori is Associated with Inflammation of Stomach which if becomes chronic there is High chance of developing into Gastric Carcinoma (Camargo, M. C., et al 2019).

By Now H.pylori is the organism in stomach which has been described most.

Like other Normal Flora (microbiome), stomach Microbiome also plays important role in metabolism regulation and diseases(Pichon, M., &Burucoa, C. 2019).

Healthy microbiota:

Healthy stomach microbiota provides lot of benefits to an individual. It helps an individual in several ways like pathogen protection, immune modulation, nutrition and metabolism. Culture based studies shows that most of the individual shares common gastric microbiota. But other approaches indicates, there is interindividual microbial diversity. However diversity depends upon number of factors like diet, aging, and use of different antibiotics as well as environmental stress (Guinane, C. M., & Cotter, P. D.  2013).

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