Gastric cancer and role of H.pylori

Gastric cancer and role of H.pylori: H.pylori has two importantvirulence factors. VacA b.CagA   These both are carcinogenic in nature and these are protein in nature. The proteinVacA is present In All H.pyloriStrains. It induces pore formation and causes apoptosis…

DNA based approaches

Metagenomics:In principle, metagenomic techniques are based on the concept that the entire genetic composition of microbial communities could be sequenced and analysed in the same way as sequencing a whole genome of a pure bacterial culture(Brawner, K. M., et al…

Methods used to study stomach microbiome

Following are methods which are used to Study gastric microbiota. Culturing based methods: Culture based methods are used to study the composition of gastric microbiota. This method focusses on easy to culture gastric microbes. This approach is used for the…

H.pylori

H.pylori was considered as main Organism living in hostile and sterile environment of stomach.H.pylorisurvives this environment by having special adaptations. It burrows deep where PH is neutral, in addition to it also secretes ureasewhich helps it to survive in this…

The Complexity ofthe Stomach micro biome

Introduction: The word microbiota represents an ensemble of microorganisms that resides in a previously established environment. Human beings have clusters of bacteria in different parts of the body such as in the surface or deep layers of skin (skin microbiota),…

Gastric Microbiota Composition

Mostly as a significance of the belief that, ‘the stomach is a sterile organ’due to acid production, unfriendly to bacteria Study on stomach microbiota left inactive for many years,. In addition, the reflux of bile acids in the stomach, the thickness…

  The microbiomerefers to the collection of genomes from all the microorganism.The microbiome definition in biology refers to the microorganisms and their genes. The microbiome is the genetic material of all the microbes(bacteria, fungi, protozoa and viruses) that live on…