In conclusion, taking all the literature into account, it has been demonstrated that there is no evidence to support the presence of bacteria in the placenta and there is no significant relationship between the pregnancy complication like preeclampsia, SGA and preterm birth with the bacteria. However, most important pathogen called as S. agalactiae is present in the placenta of the pregnant women only about 5percent in women before the onset of labour.The placenta has sterile environment and so there is no alteration or placental microbiome because it totally not exists in the pregnant women.


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